What tardigrades teach us about life on the edge

2024-12-12T13:50:41+00:0012 December 2024|

Tardigrades are tiny creatures renowned for their ability to survive extreme conditions. Dr Witold Morek, Postdoc at the Wellcome Sanger Institute, studies tardigrade genomes to unravel their evolution. This work could help enhance scientific understanding of biodiversity and lead to innovations in medicine and biotechnology.

How the Sanger Institute and GA4GH are promoting equitable access to data and informed consent in genomics research

2024-12-10T11:50:45+00:0010 December 2024|

Policy Analyst Gemma Brown talks about the role of the Sanger Institute and the Global Alliance for Genomics and Health in ensuring data is shared responsibly and that everyone has equal access to research data. She reflects on the aligned mission of Sanger and the Alliance, the challenges in data sharing and what is being done to overcome them.

Unlocking the genetics of skin cancer

2024-11-12T11:17:26+00:0012 November 2024|

Dr David Adams, Senior Group Leader at the Wellcome Sanger Institute, is a pioneer in cancer biology and uncovering skin cancer genetics. We explore his 20-year career at Sanger and the global impact of his research.

A melody of bases: How scaling allows us to set new bars

2024-11-14T15:27:33+00:008 November 2024|

This month we are celebrating a new milestone of sequencing 50 Petabases of DNA. Large-scale sequencing projects have contributed to this achievement, providing us with unprecedented insights into human health and disease.

Unpicking the puzzle of plasmids – how bacteria share drug resistance

2024-11-07T12:48:04+00:0031 October 2024|

Arnav Lal is interested in merging clinical practice with infectious disease research. He has recently completed his year-long Master’s in Biological Science through the Churchill Scholarship, provided by the University of Cambridge. For his Master’s he conducted research at the Wellcome Sanger Institute on antimicrobial resistance and used genomics to study how bacteria pass mobile genetic elements around. We caught up with him to talk about his experiences before he moved on to his next step, beginning his studies at Harvard medical school.

AI and genome engineering: new directions in biology

2024-12-18T16:09:19+00:0024 October 2024|

Dr Leopold Parts, Group Leader at the Wellcome Sanger Institute, studies the effects of DNA mutations by engineering variation in cells. After almost 10 years at Sanger, he has worked across different research areas and experienced significant changes in the field of biology. We spoke with Leo to hear his vision for the role of AI in enhancing gene editing and how it may revolutionise generative and synthetic genomics.

Sanger Prize: The power of persistence

2024-11-07T12:51:03+00:0022 October 2024|

Meet the next generation of genomic scientists who are benefiting from the Sanger Prize. Damilola Gbore won the Prize in 2023, after first applying in 2020. He joined the Parasites and Microbes Programme to work alongside Ewan Harrison’s research group. During his three-month placement, he analysed virus sequencing data, learning the techniques that researchers can use to diagnose and track viruses in humans.

AI and the future of generative biology

2024-12-18T16:10:18+00:0017 October 2024|

Artificial intelligence (AI) is transforming biology by enabling researchers to build predictive models from vast biological datasets. Wellcome Sanger Institute researchers are leveraging AI tools to predict, design, and engineer biological sequences, such as DNA and proteins.