Sanger Science

  • 1 September 2026

    From bacterial defence to breakthrough therapies, we explore how CRISPR-Cas is transforming research and healthcare, and how experts at the Wellcome Sanger Institute are refining the technology to make genome editing more scalable and effective.

  • 25 August 202612.4 min read

    Changes in the PTEN gene, that causes PTEN hamartoma tumour syndrome (PHTS), can lead to a range of different manifestations that vary from person to person, including an increased risk of certain cancers. A new project aims to understand why some tissues in people with PHTS become cancerous, and if there is a way of identifying individuals with PTEN variants who are most at risk.

  • 20 August 20269.7 min read

    Small flies, big mysteries. Genomics can help reveal the evolutionary picture of these two-winged wonders.

  • 5 August 20268.3 min read

    Tiny organs, big story. We explore how our organoid biobank came to life – from building long-lived models to making data openly available to the research community.

  • 21 July 202610.9 min read

    There may be a series of products for it and even a musical named after it – but what do we actually know about hair? And how are researchers at the Wellcome Sanger Institute working to uncover what is really going on beneath the surface?

  • 14 July 20269.8 min read

    We are in the seventh global cholera pandemic, which has been going on since the early 1960s. But what is cholera, and why is it still a global issue? Lia Bote, PhD student at the Wellcome Sanger Institute, answers our questions about the past, present, and hopefully the future of cholera research.

  • 1 July 202612.6 min read

    Red, itchy, unpredictable – eczema is more than just a skincare issue. It is a chronic inflammatory condition that affects people’s day-to-day lives. We explore what it is, what remains unclear and how researchers at the Wellcome Sanger Institute are getting beneath the surface to find out more.

  • 16 June 202610.8 min read

    Inflammatory bowel disease (IBD) looks different for everyone who has it. We spoke with medical student, Imogen about her personal experience of living with IBD, how it has influenced her career path and how new research from the Wellcome Sanger Institute brings her hope.