Sanger Science

  • 25 September 2023

    Tumours from 1000 children with kidney cancer have been sequenced, thanks to the Little Princess Trust and researchers at the Wellcome Sanger Institute. The Little Princess Trust ‘Knowledge Bank’ is the largest comprehensive genomics resource for any childhood solid tumour, and is already being used for research to understand childhood cancers.

  • Group shot of the Mosaic Therapeutics team on the Wellcome Genome Campus
    12 September 202314.1 min read

    The Sanger Institute is committed to innovative science at scale, but we need partners and investors to transfer this science into the clinic. Mariya Chhatriwala, Business Development Manager, gives us her insights on how the Sanger Institute’s fifth spin-out company came to be.

  • 17 August 202314.2 min read

    Use this simple guide to tell your mosquitoes apart this World Mosquito Day

  • 10 August 202310.3 min read

    A gene is a string of DNA letters that encode a protein - the building blocks of our cells and bodies. One gene encodes one protein. Simple, right? But scratch the surface into the molecular details and it soon gets complicated. Ongoing research, including work by scientists at the Wellcome Sanger Institute, is unpacking some of this complexity across diverse organisms - and viruses - and helping to reshape what we mean by a “gene”.

  • Art by Uta Mackensen (CC BY-ND) Image Description: Background: A world map and chromosome idiogram. Foreground: People moving amongst and inspecting larger than life Variant Effect Maps of clinically important genes BRCA1, HMBS, MTHFR and TDP-43.
    7 August 202324.8 min read

    Mutational scanning technologies are revolutionising the way we understand human genetic variation. A symposium in July brought together researchers from over 50 countries to explore the possibilities of this incipient genomic method, and how it can benefit clinicians and patients.

  • Lee research group
    26 July 202310.1 min read

    At the end of July 2023, Dr Marcus Lee and his research group will finalise the move of their Malaria Parasite Drug Resistance programme to the University of Dundee, where he is now Professor of Parasite Molecular Genetics.

  • 26 July 20238.3 min read

    Nearly twenty three years after first joining the Wellcome Sanger Institute, at the end of July Dr Matt Berriman will complete the move of his research to the University of Glasgow, where he is now Professor of Parasitology.

  • Stylised diagram of prime editing in action
    17 July 202311.4 min read

    Prime editing is the latest technique that enables scientists to alter the DNA of a living cell. It builds on CRISPR-Cas9 technology, and offers the potential to edit human cells to treat genetic diseases.