Sanger Science
13 October 2026Clinician scientist Dr Ayesha Noorani spends her weeks seeing patients, performing complex cancer surgery and connecting the dots through her research at the Wellcome Sanger Institute. She shares how working across both sides of medicine shapes the questions she asks, strengthens her curiosity and drives her research.
30 September 202612.2 min readDeep inside the body, a hidden world of trillions of microbes is constantly at work. Here, we highlight research led by Dr Trevor Lawley’s group at the Wellcome Sanger Institute and explore surprising facts about the gut microbiome, revealing how this unseen ecosystem shapes our health.
22 September 202611.5 min readWe take an inside look into what laser capture microdissection is and how it is enabling scientists at the Wellcome Sanger Institute to precisely isolate cells and reveal detailed insights into biology and disease.
1 September 202611.8 min readFrom bacterial defence to breakthrough therapies, we explore how CRISPR-Cas is transforming research and healthcare, and how experts at the Wellcome Sanger Institute are refining the technology to make genome editing more scalable and effective.
25 August 202612.4 min readChanges in the PTEN gene, that causes PTEN hamartoma tumour syndrome (PHTS), can lead to a range of different manifestations that vary from person to person, including an increased risk of certain cancers. A new project aims to understand why some tissues in people with PHTS become cancerous, and if there is a way of identifying individuals with PTEN variants who are most at risk.
20 August 20269.7 min readSmall flies, big mysteries. Genomics can help reveal the evolutionary picture of these two-winged wonders.
5 August 20268.3 min readTiny organs, big story. We explore how our organoid biobank came to life – from building long-lived models to making data openly available to the research community.
21 July 202610.9 min readThere may be a series of products for it and even a musical named after it – but what do we actually know about hair? And how are researchers at the Wellcome Sanger Institute working to uncover what is really going on beneath the surface?
