Sanger Science

  • 1 September 2026

    From bacterial defence to breakthrough therapies, we explore how CRISPR-Cas is transforming research and healthcare, and how experts at the Wellcome Sanger Institute are refining the technology to make genome editing more scalable and effective.

  • 25 August 202612.4 min read

    Changes in the PTEN gene, that causes PTEN hamartoma tumour syndrome (PHTS), can lead to a range of different manifestations that vary from person to person, including an increased risk of certain cancers. A new project aims to understand why some tissues in people with PHTS become cancerous, and if there is a way of identifying individuals with PTEN variants who are most at risk.

  • 16 June 202610.8 min read

    Inflammatory bowel disease (IBD) looks different for everyone who has it. We spoke with medical student, Imogen about her personal experience of living with IBD, how it has influenced her career path and how new research from the Wellcome Sanger Institute brings her hope.

  • 4 June 20269.5 min read

    A climate change hotspot in Bangladesh acts as a natural laboratory for scientists aiming to study healthy human guts and gauge future disease risk.

  • 12 May 202619.4 min read

    Women’s health is underfunded and understudied. We explore how researchers across the Wellcome Sanger Institute are using advanced genomic tools to unpick the complexities of fundamental women’s health issues.

  • 9 April 202610.2 min read

    Discover how the Wellcome Sanger Institute has been at the forefront of spatial research, exploring how trillions of cells organise, communicate and work together to form a human being. For more than 15 years, Sanger scientists have pushed the boundaries of modern genomics, helping to map the human body in greater detail – cell by cell.

  • 17 March 202612.8 min read

    We explore how genomics is helping researchers at the Wellcome Sanger Institute to unpick the tangled world of parasitic worms.

  • 10 March 202610.5 min read

    Sepsis is a killer, responsible for 20 per cent of all deaths around the world. Yet the condition is notoriously difficult to study. Dr Emma Davenport and her team are using genomics to uncover the biological mechanisms at work.