The architecture of disease

2024-10-09T09:52:41+01:009 October 2024|

Our photo essay features some of the people behind the cutting-edge cancer research at the Sanger Institute. With genomic techniques now able to uncover the DNA sequence and structure in millions individual cells, they are uncovering the genetic architecture of disease.

Predicting cell responses to disease and drugs with AI

2024-12-18T16:11:59+00:0026 September 2024|

Mo Lotfollahi joined the Wellcome Sanger Institute in April as a new Group Leader in the Cellular Genetics programme. Mo works with wet lab scientists and bioinformaticians to develop generative AI models for predicting cellular responses.

Personalising cancer treatment using the gut microbiome

2024-09-06T10:23:10+01:006 September 2024|

Did you know that your gut bugs may affect your cancer risk? Dr Ashray Gunjur, Clinical Research Training Fellow at the Wellcome Sanger Institute, is exploring how clinicians can use the biology of the gut microbiome to personalise cancer treatment.

Join us for the Explainable AI in Biology Conference

2024-12-18T16:13:22+00:002 September 2024|

Science and AI fans, get ready for October 2024 – the Wellcome Sanger Institute is hosting the first-ever Explainable AI in Biology Conference at the Wellcome Genome Campus. Here we review a snapshot of some of the planned talks from AI experts about integrating AI into biological research.

Tackling power imbalances in genomics research

2024-08-24T10:19:55+01:0020 August 2024|

Embedding ethics into research enables scientists to maximise the societal benefit of their work. It is also an important tool for accountability, especially in genomics research. For instance, how are the data gathered going to serve the communities that have donated the data to research?

Families and scientists unite to drive forward rhabdomyosarcoma research

2024-08-08T09:53:04+01:008 August 2024|

Scientists and parents involved with a pioneering childhood cancer charity recently came together to discuss the future of research into the childhood cancer rhabdomyosarcoma, from its genetic causes to treatment innovations. A promising new project - co-designed by researchers and families - will now mine hundreds of biobank samples to understand the genomic and demographic factors governing how a child responds to treatment.

One (cell) to rule them all

2024-07-05T10:06:46+01:003 July 2024|

The HipSci cell lines, now searchable in a newer, user-friendly platform, are a resource used worldwide by researchers. They can be used for a wide variety of research applications, including large-scale experiments that require multiple cell lines created in a standardised manner.