Category: Sanger Science

Exploring Sanger’s groundbreaking research

A trusty guide for exploring the complexity of cells

Single cell RNA sequencing data can be used to identify cell types. Martin Hemberg and Vladimir Kiselev explain how their new scmap method can help the Human Cell Atlas initiative by analysing this data.

New computational method reveals where genes are expressed

06.04.18 Valentine Svensson explains how the new computational method SpacialDE interprets single-cell data to identify which genes are switched on in different locations, allowing researchers to zoom into the structures of tissues.

Sequencing a superbug: How typhoid became extensively drug-resistant

20.02.18 Gordon Dougan and Elizabeth Klemm report how their laboratory has been sequencing the DNA of Salmonella Typhi strains that infect people around the world, and we have found evidence for an accelerating evolution of resistance to antibiotics

Big data for mosquito control

20.12.17 Alistair Miles explains how the Anopheles gambiae 1000 Genomes project is helping to understand the evolution and spread of insecticide resistance in mosquitos across Africa, supporting the campaign to eliminate malaria.

Life in the fast lane: rapid reproduction in malaria parasites

1.12.17 Brandon Invergo investigates how quickly malaria parasites can prepare to sexually reproduce once they are picked up by a mosquito.

A step towards an effective, multi-target vaccine for malaria

Gareth Powell and Leyla Bustamante helped to find five targets on the parasite that could be the basis of a new vaccine

Results of the Chordoma Genome Project reveal genetic changes that drive chordoma

DATE: 12/09/17 By: Chordoma Foundation Team Editor’s Note: This blog is reproduced from The Chordoma Foundation blog, a charity that has funded and collaborated on recent research by Sanger Institute scientists. For more on The Chordoma Foundation, […]