Sanger Science – Wellcome Sanger Institute Blog

How Sanger Institute researchers are using caterpillars to study pneumonia

Catching pneumonia with caterpillars

March 14, 2019March 18, 2019 Sanger Institute 3Rs, animal care, animal research, bacteria, caterpillars, mice, pneumonia min read

Using caterpillars to investigate how human pneumonia works.

DNA data has turned from a trickle to a flood of information that could transform medicine and biological understanding. Ali Cranage explores how Sanger scientists are using AI to extract new discoveries and knowledge

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Getting smart about artificial intelligence

March 4, 2019March 4, 2019 cc13sangeracuk AI, algorithms, artificial intelligence, computing, data, Genomics, machine learning, outbreaks, Salmonella min read

Sanger researchers are harnessing the power of AI to extract new knowledge from the ever increasing flood of genomic data. The findings could transform medicine and biological understanding.

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The weird and wonderful world of organoids

February 4, 2019February 6, 2019 Sanger Institute cancer, organoids min read

Mini organs grown in the lab are boosting cancer research and drug discovery.

Science in a conflict zone: tracking cholera in Yemen

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Science in a conflict zone: Investigating cholera in Yemen

January 2, 2019January 23, 2019 Sanger Institute cholera, DNA, epidemic, Genetics, genomes, Genomics, medecins sans frontieres, msf, Sanger Life, Sanger Science, yemen min read

In addition to the civil war, Yemen is experiencing the worst epidemic of cholera ever recorded. We spoke to Ankur Rakesh, a volunteer doctor with Médecins Sans Frontières (MSF) / Doctors Without Borders, who travelled to Yemen in July 2017 to study the genomics of this highly infectious and deadly disease

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Solving the mysteries of developmental disorders: The DDD study

October 16, 2018October 16, 2018 Communications Team data, DDD, deciphering developmental disorders, DNA, health, human health, rare disease, Sanger Science, sequencing min read

Alison Cranage talks to one family who have been helped by the Deciphering Developmental Disorders study

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25 years of pushing the scientific boundaries

October 1, 2018January 15, 2019 Communications Team 25 years, data, DNA, gorilla, Human Cell Atlas, human genetics, human genome project, Infectious disease, Influencing Policy, Sanger Science, sequencing, tree of life min read

From one human genome to hundreds of thousands, to every single cell in the body, to the genome of every species on the planet – DNA sequencing is accelerating. On our 25th anniversary we look at the evolution, application and potential of this powerful science.

Mosquito in close up. Image credit: CDC/Dr Paul Howell

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Building capacity for genomic surveillance of malaria mosquitoes in Africa

September 21, 2018January 15, 2019 Communications Team malaria, mosquito, Sanger Science min read

Funding from the Bill and Melinda Gates Foundation will enable the Pan African Mosquito Control Association (PAMCA) to launch nine new projects for mosquito genomics researchers across Africa. The Sanger Institute will sequence 500 mosquito genomes from each study. The deadline for research applications is 3 October 2018

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Sequencing a superbug: How typhoid became extensively drug-resistant

February 20, 2018June 29, 2018 Communications Team min read

20.02.18 Gordon Dougan and Elizabeth Klemm report how their laboratory has been sequencing the DNA of Salmonella Typhi strains that infect people around the world, and we have found evidence for an accelerating evolution of resistance to antibiotics

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Big data for mosquito control

December 20, 2017June 29, 2018 Communications Team min read

20.12.17 Alistair Miles explains how the Anopheles gambiae 1000 Genomes project is helping to understand the evolution and spread of insecticide resistance in mosquitos across Africa, supporting the campaign to eliminate malaria.