The history of spatial transcriptomics at Sanger

2026-04-09T09:43:44+01:009 April 2026|

Discover how the Wellcome Sanger Institute has been at the forefront of spatial research, exploring how trillions of cells organise, communicate and work together to form a human being. For more than 15 years, Sanger scientists have pushed the boundaries of modern genomics, helping to map the human body in greater detail – cell by cell.

What the hel-minth?

2026-03-12T15:13:53+00:0017 March 2026|

We explore how genomics is helping researchers at the Wellcome Sanger Institute to unpick the tangled world of parasitic worms.

Decoding sepsis and the secrets of the immune system

2026-03-09T10:48:21+00:0010 March 2026|

Sepsis is a killer, responsible for 20 per cent of all deaths around the world. Yet the condition is notoriously difficult to study. Dr Emma Davenport and her team are using genomics to uncover the biological mechanisms at work.

Ways Sanger is applying spatial transcriptomics to our science

2026-01-26T11:55:56+00:0027 January 2026|

Imagine being able to pinpoint exactly where in an aggressive brain tumour certain genes are turned on – like mapping a city’s most active neighbourhoods at rush hour. That is the promise of spatial transcriptomics, breakthrough technologies that are changing how scientists understand tissues, health and disease, and development.

What are somatic mutations?

2026-01-15T11:52:25+00:0015 January 2026|

When most people think about genetic changes, or mutations, they imagine inherited conditions that are passed on from parents to offspring. However, the vast majority of mutations in our DNA are not inherited at all. Instead, they arise quietly, cell-by-cell throughout our lifetime. These are somatic mutations, and they are one of the most important – yet least understood – forces acting inside our bodies.

Understanding respiratory viruses in the age of the ‘super flu’

2025-12-23T12:19:23+00:0023 December 2025|

For many, flu season has come earlier this year with hospitalisations rising by more than 50 per cent in one week in the UK. The so-called ‘super flu’ is causing a media frenzy – but what actually is it? Why are we seeing it earlier than usual? And how can we be better prepared in the future?

Five questions on butterfly and moth genomics with Charlotte Wright

2025-12-12T16:02:08+00:0011 December 2025|

Drawn to genomics like a moth to a flame, Wellcome Sanger Institute Postdoctoral Fellow, Dr Charlotte Wright, shares with us how she uses genomics to shed light on the evolutionary history of butterflies and moths, and how they might change in the future.