Sanger Science
8 August 2024Scientists and parents involved with a pioneering childhood cancer charity recently came together to discuss the future of research into the childhood cancer rhabdomyosarcoma, from its genetic causes to treatment innovations. A promising new project - co-designed by researchers and families - will now mine hundreds of biobank samples to understand the genomic and demographic factors governing how a child responds to treatment.
12 March 20134.8 min read13 March 2013: Tapeworm’s leave all the hard work to their hosts. But their laziness could be their undoing. Genome sequencing has revealed that the parasites' genetic simplicity makes them extremely reliant on certain genes and processes to live, and these 'weak spots' may be vulnerable to existing drugs
27 February 20134.7 min read27 Feb 2013: piggyBac is a jumping gene that normally leaps from TTAA sequence to TTAA sequence. But, sometimes, it lands in unexpected places, causing point mutations. Zemin Ning explains how the Sanger Institute used next-generation sequencing and a lot of computing power to chase the gene around the mouse genome to understand how it works
- 15 February 20134.7 min read
15 Feb 2013: Susana Campino explains how her lab works in partnerships to uncover the genes that make people resistant to severe malaria.
13 February 20136.3 min read13 Feb 2013: For one family at least, selective male deafness is true. A team at the Sanger Institute has discovered a mutation on the male-only Y chromosome that causes adult deafness, Yali Xue reveals…
![Bacteria that cause the sexual diseases Chlamydia and gonorrhoea can swap DNA between their peers and hide from medical tests, explains Helena Seth-Smith. Genetic sequencing may help us penetrate their camouflage [Credit: Genome Research Limited]](https://i0.wp.com/sangerinstitute.blog/wp-content/uploads/2013/02/home_chlamydia.jpg?fit=848%2C276&ssl=1 "home_chlamydia")
4 February 20133.8 min read04 Feb 2013: Bacteria that cause the sexual diseases Chlamydia and Gonorrhoea can swap DNA between their peers and hide from medical tests, explains Helena Seth-Smith. Genetic sequencing may help us penetrate their camouflage
29 January 20133.3 min read29 Jan 2013: Using genome sequences and computer analysis, we are able to understand the rapid evolution of the influenza virus, explains Chris Illingworth.
