Sanger Science

  • 20 August 2025

    Kids often have the best questions, and mosquitoes — the world’s deadliest animal — hold so many secrets. Inspired by real questions from 7-year-olds, we dive into some fascinating facts and learn what genomics can reveal about one of nature’s tiniest troublemakers.

  • 5 questions on alternative splicing with Omar El Garwany
    14 August 20258.2 min read

    What is alternative splicing, and why does it matter? Omar El Garwany, PhD student at the Wellcome Sanger Institute, is exploring how splicing differences can cause disease, providing insights that could eventually contribute to better diagnostics and therapies.

  • 26 September 202211.4 min read

    The world’s largest human genome sequencing project has been for UK Biobank – a large-scale biomedical database. Sanger staff have sequenced 243,633 human genomes in 3.5 years.

  • 26 September 20226.3 min read

    In 2019, the Sanger Institute started on the most ambitious human genome sequencing project in the world. Three years later, the Institute has delivered nearly 250,000 whole human genome sequences and over 20 petabytes (PB) of data, for the UK Biobank project, to aid research into health and disease.

  • 16 August 202211.1 min read

    Decade-long surveillance of a deadly bacterial pathogen has shown how genomics can be used to design effective vaccines and combat antimicrobial resistance.

  • 9 August 20228.1 min read

    Explore the skilful art of interpreting genome sequence data - from the human genome project to all species.

  • 3 August 202210 min read

    A decades-long interest in cell surface proteins has led to discoveries as diverse as how malaria parasites invade human blood cells, a vaccine target for a neglected tropical disease, and finding the molecules that must interact to initiate new life.

  • 30 June 20226.6 min read

    Dr Josie Bryant is a new group leader at the Sanger Institute. She is interested in how microbes in the human lung evolve and adapt over time and how this affects health and disease. We spoke to Josie about the inspirations behind her science, returning to Sanger, and what excites her about establishing a new research group.