Sanger Science

Prime editing is the latest technique that enables scientists to alter the DNA of a living cell. It builds on CRISPR-Cas9 technology, and offers the potential to edit human cells to treat genetic diseases.

With a decade of experience turning mosquitoes into genomic data, Alistair Miles is a pillar of the community of entomologists and analysts that keep track of the evolutionary twists and turns of malaria mosquitoes

An interview with the Sanger Institute’s new director, Matt Hurles.

Mentoring and training early career scientists; building technology that can adapt to humid and hotter countries; finding a way of transporting anaerobic microorganisms. The pathway to accelerating microbiome research isn’t lacking challenges.

The human reference genome is the foundation of modern human genetics and genomics, underpinning most research into human health and disease. But, it has limitations - it doesn't reflect human genetic diversity. A new, pangenome reference has now been published, aiming to better represent humanity.

Every year on April 25th, we observe World Malaria Day to raise awareness and mobilise action against malaria. This year, the World Health Organisation’s call to action focuses on three key areas: investing in the global malaria response, stepping up innovation, and implementing the strategies we have now.