The human reference genome is the foundation of modern human genetics and genomics, underpinning most research into human health and disease. But, it has limitations - it doesn't reflect human genetic diversity. A new, pangenome reference has now been published, aiming to better represent humanity.
Some of our staff reflect on their experiences of working on the Human Genome Project, what it means to them, and how life at the Wellcome Sanger Institute has grown.
From one human genome to hundreds of thousands, to every single cell in the body, to the genome of every species on the planet – DNA sequencing is accelerating. On our 25th anniversary we look at the evolution, application and potential of this powerful science.