Month: February 2013

piggyBac jumping gene jumping around the mouse genome

Mouse jumping genes don’t always land where they should

27 Feb 2013: piggyBac is a jumping gene that normally leaps from TTAA sequence to TTAA sequence. But, sometimes, it lands in unexpected places, causing point mutations. Zemin Ning explains how the Sanger Institute used next-generation sequencing and a lot of computing power to chase the gene around the mouse genome to understand how it works

Malaria blood-stage parasite called schizonts in blood film

Resisting malaria

15 Feb 2013: Susana Campino explains how her lab works in partnerships to uncover the genes that make people resistant to severe malaria.

Cause of selective male deafness discovered

13 Feb 2013: For one family at least, selective male deafness is true. A team at the Sanger Institute has discovered a mutation on the male-only Y chromosome that causes adult deafness, Yali Xue reveals…

Bacteria that cause the sexual diseases Chlamydia and gonorrhoea can swap DNA between their peers and hide from medical tests, explains Helena Seth-Smith. Genetic sequencing may help us penetrate their camouflage [Credit: Genome Research Limited]

Chlamydia: Silent, Treacherous, Invisible?

04 Feb 2013: Bacteria that cause the sexual diseases Chlamydia and Gonorrhoea can swap DNA between their peers and hide from medical tests, explains Helena Seth-Smith. Genetic sequencing may help us penetrate their camouflage